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Surfactant Protein A/SP-A Polyclonal Antibody (CAB24870)

SKU:
CAB24870
€129
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Description

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Product Name:Surfactant Protein A/SP-A Polyclonal Antibody
SKU:CAB24870
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 100-248 of human SFTPA1 (NP_001158116.1).
Sequence:PAHL DEEL QATL HDFR HQIL QTRG ALSL QGSI MTVG EKVF SSNG QSIT FDAI QEAC ARAG GRIA VPRN PEEN EAIA SFVK KYNT YAYV GLTE GPSP GDFR YSDG TPVN YTNW YRGE PAGR GKEQ CVEM YTDG QWND RNCL YSRL TICE F
Tested Applications:WB
Recommended Dilution:WB,1:1000 - 1:5000
Synonyms:SPA; ILD1; PSAP; PSPA; SP-A; SPA1; PSP-A; SFTP1; SP-A1; COLEC4; SFTPA1B; SP-A1 beta; SP-A1 delta; SP-A1 gamma; SP-A1 epsilon; SFTPA1
Positive Sample:Rat lung
Conjugate:Unconjugated
Cellular Localization:Secreted, extracellular matrix, extracellular space, surface film.
Calculated MW:26kDa
Observed MW:30-38kDa

This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:653509/729238
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Rat lung using Surfactant Protein A/SP-A Rabbit pAb(CAB24870) at 1:2000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:20s.

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