Surfactant Protein A/SP-A Polyclonal Antibody (CAB24870)
The Surfactant Protein A/SP-A Polyclonal Antibody (CAB24870) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting.Surfactant Protein A is a key component of the pulmonary surfactant system, playing a crucial role in lung defense and the innate immune response. Research has shown that SP-A is involved in pathogen recognition, modulation of inflammation, and regulation of immune cell function in the lungs.
This antibody is validated for use in WB applications and has demonstrated reactivity against Rat samples.
Product Name:
Surfactant Protein A/SP-A Polyclonal Antibody
SKU:
CAB24870
Size:
20μL, 100μL
Reactivity:
Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Secreted, Extracellular Matrix, Extracellular Space, Surface Film.
Calculated MW:
26kDa
Observed MW:
30-38kDa
This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
653509 729238
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Rat lung using Surfactant Protein A/SP-A Rabbit pAb (CAB24870) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time:20s.
