The SURF4 Polyclonal Antibody (CAB16744) is specifically designed for research involving the SURF4 protein, a key player in cellular protein trafficking and ER stress response. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including immunohistochemistry and flow cytometry.SURF4 is involved in the transport of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus, playing a crucial role in maintaining cellular homeostasis and proper protein folding. Dysfunction of SURF4 has been linked to ER stress and the development of various diseases, including neurodegenerative disorders and metabolic syndromes.
Therefore, studying the function of SURF4 with the use of this antibody is essential for advancing research in areas such as cell biology and disease pathogenesis.With its specificity and reliability, the SURF4 Polyclonal Antibody (CAB16744) is a valuable tool for researchers investigating the role of SURF4 in health and disease, paving the way for potential therapeutic interventions targeting protein trafficking pathways.
Product Name:
SURF4 Rabbit Polyclonal Antibody
SKU:
CAB16744
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SURF4 (NP_001267719.1).
This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat protein I to the cytosol. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6836
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using SURF4 Rabbit pAb (CAB16744) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
