SURF1 Rabbit Polyclonal Antibody (CAB6758)
- SKU:
- CAB6758
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SURF1 Rabbit Polyclonal Antibody |
SKU: | CAB6758 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-275 of human SURF1 (NP_003163.1). |
Sequence: | QVQR RKWK LNLI AELE SRVL AEPV PLPA DPME LKNL EYRP VKVR GCFD HSKE LYMM PRTM VDPV REAR EGGL ISSS TQSG AYVV TPFH CTDL GVTI LVNR GFVP RKKV NPET RQKG QIEG EVDL IGMV RLTE TRQP FVPE NNPE RNHW HYRD LEAM ARIT GAEP IFID ANFQ STVP GGPI GGQT RVTL RNEH LQYI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SHY1; CMT4K; MC4DN1; SURF1 |
Positive Sample: | SW480,HL-60,BT-474,SKOV3,U-251MG,Mouse liver,Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion inner membrane, Multi-pass membrane protein. |
Calculated MW: | 33kDa |
Observed MW: | 33kDa |
This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
Purification Method: | Affinity purification |
Gene ID: | 6834 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |