The SUPT6H Polyclonal Antibody (CAB16434) is a valuable tool for researchers studying the SUPT6H protein, a key component of the RNA polymerase II transcription complex. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting SUPT6H in human samples. It has been validated for use in Western blot applications, allowing for accurate detection and analysis of SUPT6H expression in various cell types.SUPT6H is involved in the regulation of gene expression and chromatin structure, playing a crucial role in the transcriptional elongation process.
Dysregulation of SUPT6H has been linked to various diseases, including cancer, making it a promising target for further investigation. By utilizing the SUPT6H Polyclonal Antibody, researchers can gain valuable insights into the function and role of SUPT6H in cellular processes, paving the way for potential therapeutic interventions in cancer and other related conditions.
Product Name:
SUPT6H Rabbit Polyclonal Antibody
SKU:
CAB16434
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1500-1726 of human SUPT6H (NP_003161.2).
Enables histone binding activity. Involved in negative regulation of histone H3-K27 methylation and positive regulation of transcription elongation from RNA polymerase II promoter. Predicted to be located in nucleoplasm. Predicted to be part of transcription elongation factor complex. Predicted to be active in transcriptionally active chromatin.
Purification Method:
Affinity purification
Gene ID:
6830
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SUPT6H Rabbit pAb (CAB16434) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
