The SUPT3H Polyclonal Antibody (CAB18179) is a valuable tool for researchers studying the SUPT3H protein, which plays a crucial role in regulating transcription and gene expression. This rabbit-derived antibody is highly specific to human samples and is validated for use in Western blot applications. By targeting the SUPT3H protein, this antibody enables researchers to detect and analyze SUPT3H in various cell types, making it ideal for investigations in molecular biology and cancer research.SUPT3H is a key component of the SPT-ADA-GCN5 acetyltransferase (SAGA) complex, which has been implicated in the regulation of gene expression and chromatin remodeling.
Dysregulation of SUPT3H expression has been linked to various diseases, including cancer and developmental disorders. Studying the function of SUPT3H is essential for understanding its role in disease pathogenesis and identifying potential therapeutic targets.This SUPT3H Polyclonal Antibody provides researchers with a reliable tool for investigating the molecular mechanisms underlying SUPT3H-mediated gene regulation. Its high specificity and sensitivity make it a valuable asset for studies aimed at elucidating the role of SUPT3H in health and disease.
Product Name:
SUPT3H Rabbit Polyclonal Antibody
SKU:
CAB18179
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human SUPT3H (NP_852001.1).
Enables transcription coactivator activity. Involved in histone H3 acetylation and histone deubiquitination. Located in nucleoplasm. Part of SAGA complex and transcription factor TFTC complex.
Purification Method:
Affinity purification
Gene ID:
8464
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using SUPT3H Rabbit pAb (CAB18179) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.