The SUOX Polyclonal Antibody (CAB0733) is a valuable tool for researchers studying sulphite oxidase (SUOX), an essential enzyme involved in sulphur metabolism. The antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SUOX protein, this antibody allows for the detection and analysis of SUOX in a variety of cell types, making it an excellent choice for studies in biochemistry and metabolic disorders.SUOX plays a crucial role in the detoxification of sulphur-containing compounds in the body, making it a key player in maintaining proper sulphur balance and preventing toxicity.
Dysregulation of SUOX activity has been implicated in various metabolic disorders and neurodegenerative diseases, making it an intriguing target for further research. By understanding the function of SUOX, researchers may uncover new insights into the pathogenesis of these conditions and develop novel therapeutic strategies to target SUOX activity.
Product Name:
SUOX Rabbit Monoclonal Antibody
SKU:
CAB0733
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SUOX (P51687).
Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.
Purification Method:
Affinity purification
Gene ID:
6821
Clone Number:
ARC2535
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat kidney, using SUOX antibody (CAB0733) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
