SUMO4 Rabbit Polyclonal Antibody (CAB7517)
- SKU:
- CAB7517
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | SUMO4 Rabbit Polyclonal Antibody |
SKU: | CAB7517 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human SUMO4 (NP_001002255.1). |
Sequence: | MANE KPTE EVKT ENNN HINL KVAG QDGS VVQF KIKR QTPL SKLM KAYC EPRG LSVK QIRF RFGG QPIS GTDK PAQL EMED EDTI DVFQ QPTG GVY |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | IDDM5; SMT3H4; SUMO-4; dJ281H8.4; SUMO4 |
Positive Sample: | HepG2,MCF7,Mouse kidney,Mouse spleen,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | nucleus |
Calculated MW: | 11kDa |
Observed MW: | 15kDa |
This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.
Purification Method: | Affinity purification |
Gene ID: | 387082 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |