The SUMO3 Polyclonal Antibody (CAB15724) is a vital tool for researchers studying the SUMO3 protein, which plays a crucial role in the regulation of various cellular processes, including protein stability, DNA repair, and gene expression. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SUMO3, a member of the Small Ubiquitin-like Modifier (SUMO) protein family, is involved in post-translational modification of target proteins, regulating their cellular localization, activity, and interactions. It is essential for the maintenance of genomic stability and proper cell function.
The SUMO3 Polyclonal Antibody enables researchers to detect and analyze the levels and localization of SUMO3 in different cell types, offering insights into its functions in various physiological and pathological conditions.The detailed understanding of SUMO3 protein and its regulatory pathways is critical for advancing research in areas such as cancer biology, neurodegenerative diseases, and metabolic disorders. By studying the role of SUMO3 in cellular processes, researchers can uncover new therapeutic targets and develop innovative treatments for a range of diseases.
Product Name:
SUMO3 Rabbit Polyclonal Antibody
SKU:
CAB15724
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human SUMO3 (NP_008867.2).
U-87MG,LO2,293T,Mouse liver,Mouse kidney,Mouse small intestine,Mouse heart,Rat liver,Rat heart
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus, PML body.
Calculated MW:
12kDa
Observed MW:
17-50kDa
This gene encodes a member of the small ubiquitin-related modifier (SUMO) family of eukaryotic proteins. The encoded protein is covalently conjugated to other proteins via a post-translation modification known as sumoylation. Sumoylation may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Alternatively spliced transcript variants encoding distinct proteins have been described.
Purification Method:
Affinity purification
Gene ID:
6612
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SUMO3 Rabbit pAb (CAB15724) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
