The Sumo2/3 Rabbit Monoclonal Antibody (CAB5066) is a cutting-edge research tool designed for the study of Sumo2/3, small ubiquitin-like modifiers that play key roles in regulating various cellular processes such as DNA repair, transcriptional regulation, and protein degradation. This antibody, generated in rabbits, demonstrates high specificity and sensitivity in detecting Sumo2/3 proteins in human samples.Validated for use in Western blot applications, the Sumo2/3 Rabbit Monoclonal Antibody (CAB5066) binds specifically to Sumo2/3 proteins, enabling precise detection and analysis in a variety of cell types. Its reliability and accuracy make it an ideal tool for researchers in the fields of molecular biology, cell biology, and cancer research.
Sumo2/3 proteins have been implicated in a wide range of diseases, including cancer, neurodegenerative disorders, and viral infections. By studying the function and regulation of Sumo2/3 proteins using this antibody, researchers can gain valuable insights into the underlying mechanisms of these diseases and potentially identify new therapeutic targets. The Sumo2/3 Rabbit Monoclonal Antibody (CAB5066) is a valuable asset for any laboratory conducting research in the fields of molecular and cellular biology.
Product Name:
SUMO2/3 Rabbit Monoclonal Antibody
SKU:
CAB5066
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-95 of human SUMO2/3 (P61956).
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
6612/6613
Clone Number:
ARC1186
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SUMO2/3 Rabbit mAb (CAB5066) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
