The SUMO1 Rabbit Monoclonal Antibody (CAB19121) is a powerful tool for research involving SUMO1, a small ubiquitin-like modifier protein that plays a crucial role in cellular processes such as protein stability, localization, and interactions. This antibody, produced using rabbit monoclonal technology, exhibits high specificity and sensitivity for detecting SUMO1 in human samples, making it ideal for use in Western blotting and immunohistochemistry applications.SUMO1 is involved in the regulation of various biological pathways, including DNA repair, transcriptional activation, and signal transduction. Dysregulation of SUMOylation has been implicated in the development of cancer, neurodegenerative diseases, and viral infections.
By targeting SUMO1 with this antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for drug development.Furthermore, the use of this SUMO1 antibody allows for precise and accurate detection of SUMO1 levels in different cell types and experimental conditions, making it a valuable tool for studies in molecular biology, cell signaling, and disease mechanisms. Its reliability and performance make it an essential reagent for scientists conducting cutting-edge research in the fields of cancer biology, neurology, and virology.
Product Name:
SUMO1 Rabbit Monoclonal Antibody
SKU:
CAB19121
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-101 of human Sumo 1 (P63165).
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.
Purification Method:
Affinity purification
Gene ID:
7341
Clone Number:
ARC0215
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] SUMO1 Rabbit mAb (CAB19121) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
