SUMF2 Rabbit Polyclonal Antibody (CAB17671)
- SKU:
- CAB17671
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SUMF2 Rabbit Polyclonal Antibody |
SKU: | CAB17671 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 45-320 of human SUMF2 (NP_056226.2). |
Sequence: | QATS MVQL QGGR FLMG TNSP DSRD GEGP VREA TVKP FAID IFPV TNKD FRDF VREK KYRT EAEM FGWS FVFE DFVS DELR NKAT QPMK SVLW WLPV EKAF WRQP AGPG SGIR ERLE HPVL HVSW NDAR AYCA WRGK RLPT EEEW EFAA RGGL KGQV YPWG NWFQ PNRT NLWQ GKFP KGDK AEDG FHGV SPVN AFPA QNNY GLYD LLGN VWEW TASP YQAA EQDM RVLR GASW IDTA DGSA NHRA RVTT RMGN TPDS ASDN LGFR CAAD AGRP PGEL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | pFGE; SUMF2 |
Positive Sample: | U-87MG,A-549,HepG2,BxPC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | endoplasmic reticulum, endoplasmic reticulum lumen |
Calculated MW: | 34kDa |
Observed MW: | 34kDa |
The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 25870 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |