The SULT2B1 Polyclonal Antibody (CAB7736) is a valuable tool for researchers studying SULT2B1, an enzyme involved in the sulfonation of hormones and xenobiotics. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SULT2B1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in endocrinology, drug metabolism, and related fields.
SULT2B1, also known as sulfotransferase 2B1, plays a crucial role in the metabolism and elimination of various compounds in the body, including steroid hormones and drugs. Dysregulation of SULT2B1 activity has been linked to disorders such as hormone-dependent cancers, metabolic diseases, and drug toxicities. By studying the function and expression of SULT2B1, researchers can gain insights into these conditions and potentially identify new therapeutic targets for intervention.
Product Name:
SULT2B1 Rabbit Polyclonal Antibody
SKU:
CAB7736
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human SULT2B1 (NP_814444.1).
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
6820
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells using SULT2B1 Rabbit pAb(CAB7736) at 1:1000 dilution.Secondary antibody:(AS014 ) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:10s.
