The SULT2A1 Polyclonal Antibody (CAB14063) is a valuable tool for researchers studying SULT2A1, an enzyme responsible for sulfating steroids and xenobiotic compounds. Raised in rabbits, this antibody has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SULT2A1 protein, this antibody enables the detection and analysis of SULT2A1 in various cell types, making it an essential resource for studies in drug metabolism, hormone regulation, and liver function.
SULT2A1 plays a crucial role in the sulfonation of hormones and drugs, impacting their bioavailability, activity, and elimination from the body. Research into SULT2A1 is essential for understanding the metabolism and regulation of steroid hormones, as well as the detoxification of xenobiotic compounds. This antibody is a valuable tool for investigating the role of SULT2A1 in various physiological and pathological processes, making it a valuable asset for studies in pharmacology, endocrinology, and toxicology.
Product Name:
SULT2A1 Rabbit Polyclonal Antibody
SKU:
CAB14063
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human SULT2A1 (NP_003158.2).
This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome.
Purification Method:
Affinity purification
Gene ID:
6822
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse skeletal muscle, using SULT2A1 Rabbit pAb (CAB14063) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 50s.