The SULT1E1 Polyclonal Antibody (CAB7452) is a valuable tool for researchers studying sulfotransferase 1E1 (SULT1E1), an enzyme involved in the sulfation of various chemicals and compounds in the body. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.SULT1E1 plays a crucial role in the metabolism of endogenous and exogenous compounds, including hormones, drugs, and xenobiotics. Dysregulation of SULT1E1 activity has been linked to various diseases, making it an important target for research in pharmacology, toxicology, and endocrinology.
By utilizing the SULT1E1 Polyclonal Antibody, researchers can detect and analyze SULT1E1 protein levels in different cell types, providing valuable insights into its function and role in various physiological processes. This antibody is a valuable tool for studies investigating drug metabolism, hormone regulation, and the impact of SULT1E1 dysregulation on human health.
Product Name:
SULT1E1 Rabbit Polyclonal Antibody
SKU:
CAB7452
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-294 of human SULT1E1 (NP_005411.1).
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.
Purification Method:
Affinity purification
Gene ID:
6783
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SULT1E1 antibody (CAB7452) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
