The SULT1A3 Polyclonal Antibody (CAB12357) is a valuable tool for researchers studying SULT1A3, an enzyme involved in the metabolism of various endogenous and exogenous compounds. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SULT1A3 protein, this antibody enables the detection and analysis of SULT1A3 in a variety of cell types, making it an ideal choice for investigations in the fields of pharmacology, toxicology, and drug metabolism.
SULT1A3 plays a crucial role in the conjugation and detoxification of xenobiotics, as well as the regulation of steroid hormones and neurotransmitters. Understanding the function and regulation of SULT1A3 is important for developing strategies to optimize drug efficacy and minimize toxicity in clinical settings. This antibody offers researchers a reliable tool for studying the expression and activity of SULT1A3 in various biological samples, contributing to advancements in personalized medicine and drug development.
Product Name:
SULT1A3 Rabbit Polyclonal Antibody
SKU:
CAB12357
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SULT1A3 (NP_808220.1).
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. This gene is the most centromeric of the four sulfotransferase genes. Read-through transcription exists between this gene and the upstream SLX1A (SLX1 structure-specific endonuclease subunit homolog A) gene that encodes a protein containing GIY-YIG domains.
Purification Method:
Affinity purification
Gene ID:
6818
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SULT1A3 Rabbit pAb (CAB12357) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
