The SULT1A3 Polyclonal Antibody (PACO12577) is a valuable tool for researchers studying SULT1A3, a critical enzyme involved in the sulfation of various compounds in the body. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SULT1A3 protein, researchers can easily detect and analyze its presence in different cell types, making it ideal for investigations in drug metabolism and toxicology studies.SULT1A3 is an essential enzyme that plays a key role in the detoxification and metabolism of xenobiotics, drugs, and endogenous compounds.
Its involvement in sulfation pathways makes it a potential target for research in pharmacology, toxicology, and personalized medicine. Understanding the function and regulation of SULT1A3 is crucial for identifying potential drug interactions, predicting drug efficacy, and designing personalized treatment strategies for patients.Overall, the SULT1A3 Polyclonal Antibody (PACO12577) offers researchers a reliable tool for studying the role of SULT1A3 in drug metabolism, toxicology, and personalized medicine, opening up new avenues for research in these fields.
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3;SULT1A3;HAST;HAST3;M-PST;MGC117469;ST1A5;STM;SULT1A4;TL-PST ;
UniProt Protein Function:
SULT1A3: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 2.8.2.1; Energy Metabolism - sulfur; TransferaseChromosomal Location of Human Ortholog: 16p11.2Cellular Component: cytosolMolecular Function: sulfotransferase activity; aryl sulfotransferase activityBiological Process: steroid metabolic process; cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; flavonoid metabolic process; unfolded protein response; xenobiotic metabolic process; sulfation; catecholamine metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process
