The SULT1A2 Polyclonal Antibody (CAB12851) is a valuable tool for researchers studying SULT1A2, a sulfotransferase enzyme involved in the biosynthesis and metabolism of various compounds, including hormones, drugs, and xenobiotics. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.SULT1A2 plays a crucial role in the sulfonation process, which is important for the detoxification and elimination of potentially harmful substances from the body.
Dysregulation of SULT1A2 activity has been linked to various diseases, including cancer, drug metabolism disorders, and hormonal imbalances.By targeting the SULT1A2 protein, this polyclonal antibody enables researchers to study the expression and localization of the enzyme in different cell types and tissues. Understanding the function of SULT1A2 can provide valuable insights into drug metabolism, hormone regulation, and the development of targeted therapies for diseases associated with SULT1A2 dysfunction.
Product Name:
SULT1A2 Rabbit Polyclonal Antibody
SKU:
CAB12851
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-295 of human SULT1A2 (NP_001045.1).
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described.
Purification Method:
Affinity purification
Gene ID:
6799
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SULT1A2 Rabbit pAb (CAB12851) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
