The SULT1A1 Polyclonal Antibody (CAB1599) is a crucial tool for researchers studying the SULT1A1 enzyme, which plays a key role in the process of sulfonation and detoxification in the liver. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the SULT1A1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in drug metabolism, toxicology, and liver function.
SULT1A1 is an important enzyme involved in the metabolism of various drugs, toxins, and endogenous compounds in the body. Understanding its function and regulation is critical for assessing drug safety, predicting drug interactions, and developing personalized medicine approaches. The SULT1A1 Polyclonal Antibody provides researchers with a reliable tool to investigate the expression and activity of SULT1A1 in different biological samples, paving the way for advancements in drug development and patient care.
Product Name:
SULT1A1 Rabbit Polyclonal Antibody
SKU:
CAB1599
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human SULT1A1 (NP_803565.1).
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
6817
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SULT1A1 antibody (CAB1599) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
