The SLC26A2 Polyclonal Antibody (CAB14561) is a crucial tool for researchers studying the SLC26A2 protein, also known as diastrophic dysplasia sulfate transporter. This antibody, developed using rabbit immunization, exhibits high reactivity with human samples and has been validated for Western blot applications.SLC26A2 is a vital transporter protein involved in sulfate uptake and extracellular matrix maintenance. Mutations in the SLC26A2 gene have been associated with a range of skeletal dysplasias, underscoring the importance of studying this protein for understanding bone and cartilage development.
This antibody binds specifically to SLC26A2, enabling its detection and analysis in various cell types.Research into SLC26A2 is essential for uncovering its role in skeletal development and homeostasis, as well as its implications in skeletal disorders and therapeutic interventions. The SLC26A2 Polyclonal Antibody is a valuable tool for scientists exploring these areas and seeking to make advancements in musculoskeletal research.
Product Name:
SLC26A2 Rabbit Polyclonal Antibody
SKU:
CAB14561
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-111 of human SLC26A2 (NP_000103.2).
The diastrophic dysplasia sulfate transporter is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias. It apparently is critical in cartilage for sulfation of proteoglycans and matrix organization.
Purification Method:
Affinity purification
Gene ID:
1836
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC26A2 Rabbit pAb (CAB14561) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
