SULF1 Rabbit Polyclonal Antibody (CAB13797)
- SKU:
- CAB13797
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | SULF1 Rabbit Polyclonal Antibody |
SKU: | CAB13797 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 480-610 of human SULF1 (NP_001121676.1). |
Sequence: | SDLL TVRQ STRN LYAR GFHD KDKE CSCR ESGY RASR SQRK SQRQ FLRN QGTP KYKP RFVH TRQT RSLS VEFE GEIY DINL EEEE ELQV LQPR NIAK RHDE GHKG PRDL QASS GGNR GRML ADSS NAVG PPT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SULF-1; SULF1 |
Positive Sample: | HepG2,MCF7,PC-3,U-251MG,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell surface, Endoplasmic reticulum, Golgi apparatus, Golgi stack. |
Calculated MW: | 101kDa |
Observed MW: | 101kDa |
This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23213 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |