SUCNR1 Antibody (PACO30214)
- SKU:
- PACO30214
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
SUCNR1 Antibody (PACO30214)
The SUCNR1 Polyclonal Antibody (PAC030214) is a valuable tool for research focused on SUCNR1, a G protein coupled receptor involved in various physiological processes, including immune regulation, inflammation, and metabolism. The antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and is validated for use in Western blotting and immunohistochemistry applications.SUCNR1, also known as succinate receptor 1, has been implicated in the regulation of immune cell function and has been shown to play a role in metabolic processes through its interaction with succinate, a key metabolite in the tricarboxylic acid cycle. Research on SUCNR1 is particularly relevant in the fields of immunology, inflammation, and metabolic disorders, making this antibody a valuable tool for studying the role of SUCNR1 in various physiological and pathological conditions.
Furthermore, understanding the function of SUCNR1 may have implications for the development of therapeutic strategies targeting immune regulation, inflammation, and metabolism. By facilitating the detection and analysis of SUCNR1 in different cell types and tissues, the SUCNR1 Polyclonal Antibody enables researchers to further explore the mechanisms underlying SUCNR1-mediated signaling pathways and its potential as a therapeutic target in various diseases.
| Antibody Name: | SUCNR1 Antibody (PACO30214) |
| Antibody SKU: | PACO30214 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Succinate receptor 1 protein (303-334AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: SUCNR1 antibody at 6µg/ml + Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 39 kDa Observed band size: 39 kDa . |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO30214 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO30214 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Receptor for succinate. |
| Synonyms: | Succinate receptor 1 (G-protein coupled receptor 91) (P2Y purinoceptor 1-like), SUCNR1, GPR91 |
| UniProt Protein Function: | SUCNR1: Receptor for succinate. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-passChromosomal Location of Human Ortholog: 3q25.1Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q9BXA5 |
| NCBI GenInfo Identifier: | 47271392 |
| NCBI Gene ID: | 56670 |
| NCBI Accession: | NP_149039.2 |
| UniProt Secondary Accession: | Q9BXA5,Q8TDQ8, A8K305 |
| UniProt Related Accession: | Q9BXA5 |
| Molecular Weight: | |
| NCBI Full Name: | succinate receptor 1 |
| NCBI Synonym Full Names: | succinate receptor 1 |
| NCBI Official Symbol: | SUCNR1Â Â |
| NCBI Official Synonym Symbols: | GPR91Â Â |
| NCBI Protein Information: | succinate receptor 1 |
| UniProt Protein Name: | Succinate receptor 1 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 91; P2Y purinoceptor 1-like |
| Protein Family: | |
| UniProt Gene Name: | SUCNR1Â Â |
| UniProt Entry Name: | SUCR1_HUMAN |
| Antibodies |
| SUCNR1 Antibody (PACO04783) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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