The SUCLG1 Polyclonal Antibody (CAB15345) is a valuable tool for researchers studying succinate-CoA ligase GDP-forming subunit 1 (SUCLG1), an enzyme involved in the tricarboxylic acid (TCA) cycle and energy production. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.SUCLG1 plays a crucial role in cellular metabolism, catalyzing the conversion of succinyl-CoA to succinate in the TCA cycle. Dysregulation of SUCLG1 has been implicated in a variety of diseases, including metabolic disorders and cancer.
By targeting SUCLG1 with this antibody, researchers can investigate its expression levels and localization in different cell types, aiding in the understanding of its function and potential therapeutic implications.Overall, the SUCLG1 Polyclonal Antibody (CAB15345) is a valuable tool for researchers interested in studying the role of SUCLG1 in cellular metabolism and its implications for human health and disease.
Product Name:
SUCLG1 Rabbit Polyclonal Antibody
SKU:
CAB15345
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 41-346 of human SUCLG1 (NP_003840.2).
This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.
Purification Method:
Affinity purification
Gene ID:
8802
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SUCLG1 Rabbit pAb (CAB15345) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
