SUCLA2 Rabbit Polyclonal Antibody (CAB10040)
- SKU:
- CAB10040
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | SUCLA2 Rabbit Polyclonal Antibody |
SKU: | CAB10040 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SUCLA2 (NP_003841.1). |
Sequence: | MAAS MFYG RLVA VATL RNHR PRTA QRAA AQVL GSSG LFNN HGLQ VQQQ QQRN LSLH EYMS MELL QEAG VSVP KGYV AKSP DEAY AIAK KLGS KDVV IKAQ VLAG GRGK GTFE SGLK GGVK IVFS PEEA KAVS SQMI GKKL FTKQ TGEK GRIC NQVL VCER KYPR REYY FAIT MERS FQGP |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | A-SCS; A-BETA; MTDPS5; LINC00444; SCS-betaA; SUCLA2 |
Positive Sample: | 293T,SW480,HeLa,Mouse heart,Mouse liver,Mouse brain,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 50kDa |
Observed MW: | 50kDa |
Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
Purification Method: | Affinity purification |
Gene ID: | 8803 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |