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STXBP6 Antibody (PACO12568)

SKU:
PACO12568
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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STXBP6 Antibody (PACO12568)

The STXBP6 Polyclonal Antibody (PACO12568) is a valuable tool for researchers studying STXBP6, a protein known for its role in regulating membrane fusion and neurotransmitter release in cells. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the STXBP6 protein, this antibody allows for the detection and analysis of STXBP6 in a variety of cell types, making it ideal for research in neuroscience and cell biology.

STXBP6, also known as syntaxin binding protein 6, plays a crucial role in the process of vesicle docking and fusion, which is essential for neurotransmission and cell communication. Dysfunction in STXBP6 has been associated with various neurological disorders, making it a promising target for further investigation. By studying STXBP6, researchers can gain insight into the mechanisms underlying these disorders and potentially identify new therapeutic targets for treatment.

Antibody Name:STXBP6 Antibody (PACO12568)
Antibody SKU:PACO12568
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human STXBP6
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:syntaxin binding protein 6 (amisyn);STXBP6;FLJ39638;HSPC156;amisyn ;
UniProt Protein Function:STXBP6: Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: exocyst; plasma membrane

Molecular Function:GTP-Rho binding; phosphatidylinositol-4,5-bisphosphate binding

Biological Process: exocyst localization; Golgi to plasma membrane transport; negative regulation of exocytosis

NCBI Summary:STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation (Scales et al., 2002 [PubMed 12145319]).[supplied by OMIM, Mar 2008]
UniProt Code:Q8NFX7
NCBI GenInfo Identifier:34222907
NCBI Gene ID:29091
NCBI Accession:Q8NFX7.2
UniProt Secondary Accession:Q8NFX7,Q8N3H1, Q8N8D5, Q96GF3, Q9P008, D3DS78,
UniProt Related Accession:Q8NFX7
Molecular Weight:11,587 Da
NCBI Full Name:Syntaxin-binding protein 6
NCBI Synonym Full Names:syntaxin binding protein 6
NCBI Official Symbol:STXBP6  
NCBI Official Synonym Symbols:amisyn; HSPC156  
NCBI Protein Information:syntaxin-binding protein 6
UniProt Protein Name:Syntaxin-binding protein 6
UniProt Synonym Protein Names:Amisyn
Protein Family:Syntaxin-binding protein
UniProt Gene Name:STXBP6  
UniProt Entry Name:STXB6_HUMAN

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