The STXBP3 Polyclonal Antibody (CAB8153) is a valuable tool for researchers studying STXBP3, a crucial protein involved in regulating vesicle trafficking and neurotransmitter release. This antibody, produced in rabbits, is highly specific and reacts strongly with STXBP3 in human samples, making it ideal for use in Western blot applications.STXBP3, also known as Munc18-3, plays a pivotal role in synaptic vesicle fusion and neurotransmitter release in neurons. Dysfunction of STXBP3 has been linked to various neurological disorders, including epilepsy and intellectual disability.
By targeting STXBP3 with this antibody, researchers can gain insights into the mechanisms underlying these conditions and potentially uncover novel therapeutic targets.With its high reactivity and specificity, the STXBP3 Polyclonal Antibody (CAB8153) is a valuable tool for unraveling the complex biology of STXBP3 and its implications in neurological diseases. Researchers can rely on this antibody to detect and analyze STXBP3 expression in a variety of cell types, paving the way for advancements in neuroscience research.
Product Name:
STXBP3 Rabbit Polyclonal Antibody
SKU:
CAB8153
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 343-592 of human STXBP3 (NP_009200.2).
Enables syntaxin binding activity. Involved in negative regulation of calcium ion-dependent exocytosis; neutrophil degranulation; and platelet aggregation. Located in cytosol; plasma membrane; and secretory granule. Is active in presynapse.
Purification Method:
Affinity purification
Gene ID:
6814
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STXBP3 antibody (CAB8153) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
