The STXBP2 Polyclonal Antibody (CAB7735) is a valuable tool for researchers studying STXBP2, a key protein involved in regulating membrane fusion and neurotransmitter release. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the STXBP2 protein, this antibody enables researchers to detect and analyze STXBP2 expression in a variety of cell types.STXBP2, also known as syntaxin-binding protein 2, plays a crucial role in controlling the release of neurotransmitters at synapses, making it essential for proper neuronal communication.
Dysregulation of STXBP2 has been linked to neurological disorders such as autism spectrum disorder and epilepsy, highlighting the importance of studying this protein in both normal and pathological conditions.By using the STXBP2 Polyclonal Antibody, researchers can gain valuable insights into the function of STXBP2 and its implications in neurological diseases. This antibody is a powerful tool for advancing our understanding of neurotransmitter release mechanisms and developing potential therapies for neurological disorders.
Product Name:
STXBP2 Rabbit Polyclonal Antibody
SKU:
CAB7735
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_001120868.1).
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
6813
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STXBP2 antibody (CAB7735) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
