STXBP2 Rabbit Polyclonal Antibody (CAB12511)
- SKU:
- CAB12511
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | STXBP2 Rabbit Polyclonal Antibody |
SKU: | CAB12511 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_001120868.1). |
Sequence: | MAPS GLKA VVGE KILS GVIR SVKK DGEW KVLI MDHP SMRI LSSC CKMS DILA EGIT IVED INKR REPI PSLE AIYL LSPT EKAL IKDF QGTP TFTY KAAH IFFT DTCP EPLF SELG RSRL AKVV KTLK EIHL AFLP YEAQ VFSL DAPH STYN LYCP FRAE ERTR QLEV LAQQ IATL CATL QEYP AIRY RKGP EDTA QLAH AVLA KLNA FKAD TPSL GEGP EKTR SQLL IMDR AADP VSPL LHEL TFQA MAYD LLDI EQDT YRYE TTGL SEAR EKAV LLDE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FHL5; UNC18B; Hunc18b; UNC18-2; pp10122; unc-18B; MUNC18-2; STXBP2 |
Positive Sample: | THP-1,Jurkat,Mouse testis,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | azurophil granule, cytolytic granule, cytosol, extracellular exosome, extracellular region, plasma membrane, presynapse |
Calculated MW: | 66kDa |
Observed MW: | 66kDa |
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6813 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |