The STXBP2 Polyclonal Antibody (CAB12511) is a valuable tool for researchers studying STXBP2, a protein involved in vesicle trafficking and membrane fusion processes within cells. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the STXBP2 protein, this antibody enables the detection and analysis of STXBP2 in a variety of cell types, making it ideal for studies in cell biology and neuroscience.
STXBP2, also known as syntaxin-binding protein 2, plays a crucial role in regulating neurotransmitter release and synaptic transmission in the brain. Dysregulation of STXBP2 has been implicated in various neurological disorders, making it a compelling target for research aimed at understanding the molecular mechanisms underlying these conditions. By gaining insights into the function of STXBP2, researchers can pave the way for the development of novel therapeutic approaches for neurological diseases.
Product Name:
STXBP2 Rabbit Polyclonal Antibody
SKU:
CAB12511
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_001120868.1).
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
6813
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STXBP2 antibody (CAB12511) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
