The STXBP1 Rabbit Monoclonal Antibody (CAB9309) is an essential tool for researchers studying the STXBP1 protein, a key regulator of synaptic vesicle exocytosis. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in Western blot applications. By binding to the STXBP1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable resource for studies in neuroscience and neurology.STXBP1, also known as syntaxin-binding protein 1, is crucial for neurotransmitter release and synaptic transmission, playing a pivotal role in neuronal communication and brain function.
Dysregulation of STXBP1 has been implicated in various neurological disorders, including epilepsy, intellectual disability, and autism spectrum disorders. Investigating the function of STXBP1 can provide important insights into the mechanisms underlying these conditions and may lead to the development of targeted therapies.In summary, the STXBP1 Rabbit Monoclonal Antibody (CAB9309) is a highly reliable and specific reagent for studying STXBP1 in the context of synaptic transmission and neurological disorders. Its use can contribute to advancements in our understanding of brain function and the development of novel treatment strategies for neurological conditions.
Product Name:
STXBP1 Rabbit Monoclonal Antibody
SKU:
CAB9309
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human STXBP1 (P61764).
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
6812
Clone Number:
ARC1518
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using STXBP1 Rabbit mAb (CAB9309) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
