The Syntaxin 8 Polyclonal Antibody (CAB10050) is a valuable tool for researchers studying Syntaxin 8, a critical protein involved in intracellular membrane trafficking. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to Syntaxin 8, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and molecular biology.
Syntaxin 8 is a key player in the regulation of vesicle fusion events within cells, including endosome-lysosome fusion and autophagy processes. Dysfunction in Syntaxin 8 has been linked to various diseases, making it a promising target for research into neurodegenerative disorders, metabolic diseases, and infectious diseases. Understanding the role of Syntaxin 8 is essential for developing targeted therapies that could impact these conditions at the cellular level.
Product Name:
STX8 Rabbit Polyclonal Antibody
SKU:
CAB10050
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human STX8 (NP_004844.1).
The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9482
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STX8 antibody (CAB10050) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
