The STX6 Polyclonal Antibody (CAB16283) is specifically designed for research involving STX6, a protein involved in intracellular membrane trafficking. This antibody, raised in rabbits, is highly reactive with human and other mammalian samples and is validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry.STX6 is a critical regulator of vesicle trafficking and membrane fusion events within the cell. It plays a key role in the transport of cargo between the trans-Golgi network and endosomes, as well as in the recycling of endocytic vesicles. Dysregulation of STX6 has been implicated in various diseases, including neurodegenerative disorders, infectious diseases, and cancer.
By targeting STX6 with this polyclonal antibody, researchers can study the function and localization of STX6 in different cell types and tissues. This antibody enables the detection and analysis of STX6, providing valuable insights into its role in cellular processes and disease pathology. Researchers in cell biology, molecular biology, and pharmacology will find this antibody essential for their studies on membrane trafficking and intracellular signaling pathways.
Product Name:
STX6 Rabbit Polyclonal Antibody
SKU:
CAB16283
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human STX6 (NP_005810.1).
Golgi apparatus membrane, Single-pass type IV membrane protein.
Calculated MW:
29kDa
Observed MW:
35kDa
Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation; retrograde transport, endosome to Golgi; and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome; perinuclear region of cytoplasm; and trans-Golgi network. Part of SNARE complex.
Purification Method:
Affinity purification
Gene ID:
10228
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using STX6 Rabbit pAb (CAB16283) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
