STX1A Rabbit Polyclonal Antibody (CAB5570)
- SKU:
- CAB5570
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | STX1A Rabbit Polyclonal Antibody |
SKU: | CAB5570 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human STX1A (NP_004594.1). |
Sequence: | MKDR TQEL RTAK DSDD DDDV AVTV DRDR FMDE FFEQ VEEI RGFI DKIA ENVE EVKR KHSA ILAS PNPD EKTK EELE ELMS DIKK TANK VRSK LKSI EQSI EQEE GLNR SSAD LRIR KTQH STLS RKFV EVMS EYNA TQSD YRER CKGR IQRQ LEIT GRTT TSEE LEDM LESG NPAI FASG IIMD SSIS KQAL SEIE TRHS EIIK LENS IREL HDMF MDMA MLVE SQGE MIDR IEYN VEHA VDYV ERAV SDTK KAVK YQSK ARRK KIMI IICC VILG IVIA STVG GIFA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | STX1; HPC-1; P35-1; SYN1A; STX1A |
Positive Sample: | U-251MG,HT-1080,BT-474 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasmic vesicle, Secreted, Single-pass type IV membrane protein, secretory vesicle, synapse, synaptic vesicle membrane, synaptosome. |
Calculated MW: | 33kDa |
Observed MW: | 33kDa |
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6804 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |