The STX19 Polyclonal Antibody (PAC017201) is a valuable tool for researchers studying STX19, a protein involved in intracellular vesicle trafficking. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By targeting the STX19 protein, this antibody enables the detection and analysis of STX19 in various cell types, making it ideal for studies in cell biology and molecular biology.STX19 is a key player in the regulation of vesicle transport within cells, impacting processes such as protein secretion and membrane repair.
Research on STX19 can provide insight into cellular mechanisms involved in various diseases, including neurological disorders, metabolic conditions, and viral infections. Understanding the function of STX19 is essential for developing targeted therapies that aim to modulate intracellular trafficking pathways for therapeutic benefit.
Gel: 10%SDS-PAGE, Lysate: 80 μg, Lane: 231 cell, Primary antibody: PACO17201(STX19 Antibody) at dilution 1/800 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17201(STX19 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Syntaxin 19, also known as STX19, is a 294 amino acid, peripheral membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the syntaxin family, suggesting a role in synaptic vesicle fusion. The gene encoding Syntaxin 19 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Synonyms:
syntaxin 19
UniProt Protein Function:
STX19: Belongs to the syntaxin family.Chromosomal Location of Human Ortholog: 3q11Cellular Component: integral to membrane; plasma membrane; SNARE complex; synaptic vesicleMolecular Function: protein binding; SNAP receptor activity; SNARE bindingBiological Process: intracellular protein transport; synaptic vesicle fusion to presynaptic membrane; vesicle docking
