The STX17 Polyclonal Antibody (CAB17174) is a valuable tool for researchers studying STX17, a key protein involved in vesicle trafficking and membrane fusion processes. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By targeting the STX17 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for investigations in cell biology and molecular biology research.STX17 is essential for the regulation of vesicle transport and fusion events within cells, making it a crucial player in processes such as autophagy and exocytosis.
Dysregulation of STX17 has been linked to various diseases, including neurodegenerative disorders and cancer, underscoring the importance of studying its function and mechanisms of action. By utilizing the STX17 Polyclonal Antibody, researchers can gain insight into the role of STX17 in cellular processes and potentially uncover new therapeutic targets for disease intervention.
Product Name:
STX17 Rabbit Polyclonal Antibody
SKU:
CAB17174
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human STX17 (NP_060389.2).
autophagosome, COPII-coated ER to Golgi transport vesicle, cytosol, endoplasmic reticulum-Golgi intermediate compartment, mitochondrion, plasma membrane, SNARE complex
Calculated MW:
33kDa
Observed MW:
37kDa
Enables SNAP receptor activity; SNARE binding activity; and protein phosphatase binding activity. Involved in several processes, including autophagosome membrane docking; endoplasmic reticulum to Golgi vesicle-mediated transport; and endoplasmic reticulum-Golgi intermediate compartment organization. Acts upstream of or within protein localization to phagophore assembly site. Located in several cellular components, including autophagosome membrane; endoplasmic reticulum-Golgi intermediate compartment; and mitochondria-associated endoplasmic reticulum membrane. Part of SNARE complex. Colocalizes with HOPS complex.
Purification Method:
Affinity purification
Gene ID:
55014
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Mouse heart, using STX17 antibody (CAB17174) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
