STUB1 Rabbit Polyclonal Antibody (CAB11751)
- SKU:
- CAB11751
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | STUB1 Rabbit Polyclonal Antibody |
SKU: | CAB11751 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human STUB1 (NP_005852.2). |
Sequence: | MKGK EEKE GGAR LGAG GGSP EKSP SAQE LKEQ GNRL FVGR KYPE AAAC YGRA ITRN PLVA VYYT NRAL CYLK MQQH EQAL ADCR RALE LDGQ SVKA HFFL GQCQ LEME SYDE AIAN LQRA YSLA KEQR LNFG DDIP SALR IAKK KRWN SIEE RRIH QESE LHSY LSRL IAAE RERE LEEC QRNH EGDE DDSH VRAQ QACI EAKH DKYM ADMD ELFS QVDE KRKK RDIP DYLC GKIS FELM REPC ITPS GITY DRKD IEEH LQRV GHFD PVTR SPLT QEQL IPNL AMKE VIDA FISE NGWV EDY |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | CHIP; SCA48; UBOX1; SCAR16; HSPABP2; NY-CO-7; SDCCAG7; STUB1 |
Positive Sample: | HeLa,HT-29,OVCAR3,HT-1080,Mouse brain,Mouse kidney,Rat brain,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 35kDa |
Observed MW: | 34kDa |
This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.
Purification Method: | Affinity purification |
Gene ID: | 10273 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |