The STT3B Polyclonal Antibody (CAB15574) is a valuable tool for researchers studying STT3B, a key enzyme involved in protein glycosylation. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples and is validated for use in Western blot applications. By binding specifically to the STT3B protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for studies in cell biology and biochemistry.STT3B is a catalytic subunit of the oligosaccharyltransferase (OST) complex responsible for the transfer of oligosaccharides to target proteins, a crucial post-translational modification essential for proper protein folding and function.
Dysregulation of STT3B has been implicated in various diseases, including cancer and congenital disorders of glycosylation. Therefore, understanding the function of STT3B is essential for elucidating its role in disease pathology and developing targeted therapies.Overall, the STT3B Polyclonal Antibody (CAB15574) is a reliable tool for researchers aiming to delve deeper into the intricate mechanisms of protein glycosylation and its implications in health and disease. Its specificity and sensitivity make it an invaluable asset for investigations in molecular biology, biochemistry, and biomedicine.
Product Name:
STT3B Polyclonal Antibody
SKU:
CAB15574
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STT3B (NP_849193.1).
The protein encoded by this gene is a catalytic subunit of a protein complex that transfers oligosaccharides onto asparagine residues. Defects in this gene are a cause of congenital disorder of glycosylation Ix (CDG1X).
Purification Method:
Affinity purification
Gene ID:
201595
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of HUH-7, using STT3B Rabbit pAb (CAB15574) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
