MMP11 Rabbit Polyclonal Antibody (CAB3034)
- SKU:
- CAB3034
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MMP11 Rabbit Polyclonal Antibody |
SKU: | CAB3034 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 239-488 of human MMP11 (NP_005931.2). |
Sequence: | FRYP LSLS PDDC RGVQ HLYG QPWP TVTS RTPA LGPQ AGID TNEI APLE PDAP PDAC EASF DAVS TIRG ELFF FKAG FVWR LRGG QLQP GYPA LASR HWQG LPSP VDAA FEDA QGHI WFFQ GAQY WVYD GEKP VLGP APLT ELGL VRFP VHAA LVWG PEKN KIYF FRGR DYWR FHPS TRRV DSPV PRRA TDWR GVPS EIDA AFQD ADGY AYFL RGRL YWKF DPVK VKAL EGFP RLVG PDFF GCAE PANT FL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ST3; SL-3; STMY3; MMP11 |
Positive Sample: | Raji,293T,Mouse lung,Mouse kidney,Mouse skeletal muscle,Mouse ovary,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 55kDa |
Observed MW: | 60kDa |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
Purification Method: | Affinity purification |
Gene ID: | 4320 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |