The Stromelysin-3 Polyclonal Antibody (CAB3034) is a valuable tool for researchers studying the Stromelysin-3 protein, which is known to be involved in extracellular matrix degradation and tissue remodeling. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.Stromelysin-3 is a matrix metalloproteinase that has been implicated in various physiological and pathological processes, including wound healing, tumor progression, and inflammation.
By targeting Stromelysin-3, researchers can gain insights into its role in these processes and potentially identify new therapeutic targets for diseases such as cancer and fibrosis.With its high reactivity and specificity, the Stromelysin-3 Polyclonal Antibody (CAB3034) offers researchers a reliable tool for studying the function of Stromelysin-3 in different cell types and tissues. Its versatility makes it a valuable asset for studies in fields such as cancer research, tissue engineering, and regenerative medicine.
Product Name:
MMP11 Rabbit Polyclonal Antibody
SKU:
CAB3034
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 239-488 of human MMP11 (NP_005931.2).
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
Purification Method:
Affinity purification
Gene ID:
4320
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MMP11 antibody (CAB3034) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 2min.
