The STRAP Polyclonal Antibody is a valuable tool for researchers studying STRAP, a protein known to be involved in various cellular processes including cell growth, proliferation, and survival. This antibody is raised in rabbits and is highly specific for detecting STRAP in human samples, making it ideal for use in Western blot applications.STRAP, which stands for serine/threonine kinase receptor-associated protein, is a key player in signaling pathways that regulate cell growth and survival. Dysregulation of STRAP has been linked to diseases such as cancer, making it an attractive target for therapeutic intervention.
By using the STRAP Polyclonal Antibody, researchers can accurately detect and analyze the expression levels of STRAP in different cell types, allowing for a better understanding of its role in various disease processes. This antibody is a valuable tool for studies in cell biology, cancer research, and drug development aimed at targeting STRAP for therapeutic purposes.
Product Name:
STRAP Polyclonal Antibody
SKU:
CAB21351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human STRAP (NP_009109.3).
WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
MAWD; PT-WD; UNRIP; AP
Positive Sample:
293T,HeLa
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
38kDa
Observed MW:
39kDa
Enables RNA binding activity. Involved in maintenance of gastrointestinal epithelium; negative regulation of transforming growth factor beta receptor signaling pathway; and spliceosomal snRNP assembly. Located in cytosol. Part of SMN complex. Implicated in adenocarcinoma; colorectal carcinoma; large cell carcinoma; lung carcinoma; and squamous cell neoplasm.
Purification Method:
Affinity purification
Gene ID:
11171
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type(WT) and STRAP knockout (KO) HeLa cells, using STRAP Rabbit pAb (CAB21351) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
