Anti-STRA8 Antibody (PACO18939)

Antibody Name:	STRA8 Antibody (PACO18939)
Antibody SKU:	PACO18939
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human STRA8

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18939(STRA8 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18939(STRA8 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

This gene encodes a retinoic acid, responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans.

Synonyms:

stimulated by retinoic acid, 8

UniProt Protein Function:	STRA8: Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase.Chromosomal Location of Human Ortholog: 7q33Cellular Component: cytoplasm; nucleusMolecular Function: protein dimerization activityBiological Process: fertilization; meiotic cell cycle DNA replication checkpoint; ovarian follicle development; meiotic chromosome condensation; meiotic recombination; synapsis; meiotic DNA double-strand break formation; spermatogenesis; regulation of organ growth; female meiosis sister chromatid cohesion; DNA replication; oocyte development
UniProt Protein Details:
NCBI Summary:	This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010]
UniProt Code:	Q7Z7C7
NCBI GenInfo Identifier:	74713759
NCBI Gene ID:	346673
NCBI Accession:	Q7Z7C7.1
UniProt Secondary Accession:	Q7Z7C7
UniProt Related Accession:	Q7Z7C7
Molecular Weight:	36 kd
NCBI Full Name:	Stimulated by retinoic acid gene 8 protein homolog
NCBI Synonym Full Names:	stimulated by retinoic acid 8
NCBI Official Symbol:	STRA8
NCBI Official Synonym Symbols:
NCBI Protein Information:	stimulated by retinoic acid gene 8 protein homolog
UniProt Protein Name:	Stimulated by retinoic acid gene 8 protein homolog
UniProt Synonym Protein Names:
Protein Family:	Stimulated by retinoic acid gene 8 protein
UniProt Gene Name:	STRA8
UniProt Entry Name:	STRA8_HUMAN

Antibodies

STRA8 Antibody (PACO02222)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)