The STRA6 Polyclonal Antibody (CAB12126) is a vital tool for researchers studying the STRA6 protein, a cell surface receptor involved in the transport of vitamin A. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the STRA6 protein, it enables precise detection and analysis in various cell types, making it an essential asset for studies in the fields of nutrition, metabolism, and developmental biology.STRA6 is a key player in the cellular uptake of vitamin A and its role in regulating gene expression and cellular differentiation. Its importance in vitamin A metabolism and retinoid signaling pathways highlights its relevance in various physiological and pathological processes.
Research on STRA6 is crucial for understanding the impact of vitamin A deficiency on health and development, as well as exploring potential therapeutic strategies for related disorders.Overall, the STRA6 Polyclonal Antibody is a valuable tool for researchers investigating the functions and mechanisms of the STRA6 protein in cellular processes and human health. Its specificity and reliability make it an essential component of studies aiming to unravel the complexities of vitamin A metabolism and its implications for overall well-being.
Product Name:
STRA6 Rabbit Polyclonal Antibody
SKU:
CAB12126
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 538-667 of human STRA6 (NP_071764.3).
The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
64220
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using STRA6 Rabbit pAb (CAB12126) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.