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STMN3 Antibody (PACO01553)

SKU:
PACO01553
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269

Description

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STMN3 Antibody (PACO01553)

The STMN3 Antibody (PACO01553) is a polyclonal antibody designed for research involving the STMN3 protein, which plays a crucial role in the regulation of microtubule dynamics and cell division. This antibody, raised in rabbits, is highly specific for STMN3 and is ideal for use in various applications such as Western blotting and immunofluorescence.STMN3 is a key player in cell division and is essential for the proper formation and function of the mitotic spindle. Its dysregulation has been linked to various diseases such as cancer, making it a valuable target for research in oncology and cell biology.

By using the STMN3 Antibody, researchers can accurately detect and analyze STMN3 expression in different cell types, providing valuable insights into its role in cellular processes.Furthermore, understanding the function of STMN3 can help in developing potential therapies targeting cell division in cancer treatment and other related fields. The STMN3 Antibody is a vital tool for researchers looking to further explore the mechanisms underlying cell division and microtubule dynamics, ultimately contributing to advancements in biomedical research.

Antibody Name:STMN3 Antibody
Antibody SKU:PACO01553
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:WB:1:500-1:2000
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from the Internal region of human Stathmin-3.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:STMN3; SCLIP; Stathmin-3; SCG10-like protein
UniProt Protein Function:STMN3: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3. Belongs to the stathmin family.
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 20q13.3

Cellular Component: cytoplasm; neuron projection

Molecular Function:protein domain specific binding; tubulin binding

Biological Process: cytoplasmic microtubule organization and biogenesis; microtubule depolymerization; negative regulation of Rac protein signal transduction; nervous system development; neurite development; regulation of cytoskeleton organization and biogenesis; regulation of GTPase activity

NCBI Summary:This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
UniProt Code:Q9NZ72
NCBI GenInfo Identifier:20141809
NCBI Gene ID:50861
NCBI Accession:Q9NZ72.3
UniProt Secondary Accession:Q9NZ72,O75527, Q969Y4, B3KSQ5, B7WP52, B7Z5G4,
UniProt Related Accession:Q9NZ72
Molecular Weight:19,806 Da
NCBI Full Name:Stathmin-3
NCBI Synonym Full Names:stathmin 3
NCBI Official Symbol:STMN3  
NCBI Official Synonym Symbols:SCLIP  
NCBI Protein Information:stathmin-3
UniProt Protein Name:Stathmin-3
UniProt Synonym Protein Names:SCG10-like protein
Protein Family:Stathmin
UniProt Gene Name:STMN3  
UniProt Entry Name:STMN3_HUMAN

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