The STMN1 Polyclonal Antibody (CAB14018) is a valuable tool for research involving STMN1, a protein known to play a crucial role in cell proliferation and cytoskeleton dynamics. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the STMN1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.
STMN1, also known as stathmin, is involved in microtubule dynamics and cell cycle regulation, making it a key player in processes like cell division and migration. Its dysregulation has been implicated in various cancers and neurological disorders, highlighting the importance of understanding its function. By studying STMN1 using this polyclonal antibody, researchers can gain insights into its role in disease pathogenesis and potentially identify new therapeutic targets for intervention.
Product Name:
Stathmin 1 Rabbit Polyclonal Antibody
SKU:
CAB14018
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-149 of human Stathmin 1 (NP_981944.1).
Sequence:
MASS DIQV KELE KRAS GQAF ELIL SPRS KESV PEFP LSPP KKKD LSLE EIQK KLEA AEER RKSH EAEV LKQL AEKR EHEK EVLQ KAIE ENNN FSKM AEEK LTHK MEAN KENR EAQM AAKL ERLR EKDK HIEE VRKN KESK DPAD ETEA D
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3925
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Stathmin 1 antibody (CAB14018) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
