The STK4 Polyclonal Antibody (CAB8043) is a valuable tool for researchers studying the STK4 protein, also known as serine/threonine kinase 4. This antibody, produced in rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the STK4 protein, this antibody allows for accurate detection and analysis in various cell types, making it an ideal choice for studies in cell biology, signal transduction, and cancer research.STK4 is a key regulator of cell proliferation, differentiation, and apoptosis, making it a promising target for understanding cancer development and progression.
Research into the function of STK4 could provide insights into the mechanisms underlying tumorigenesis and identify potential therapeutic strategies for cancer treatment. Additionally, STK4 has been linked to immune response regulation, suggesting its involvement in inflammatory processes and autoimmune diseases.By utilizing the STK4 Polyclonal Antibody in your research, you can explore the multifaceted roles of STK4 in various biological processes and gain valuable insights into its potential implications in human health and disease.
Product Name:
MST1/STK4 Rabbit Polyclonal Antibody
SKU:
CAB8043
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 303-487 of human MST1/STK4 (NP_006273.1).
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Purification Method:
Affinity purification
Gene ID:
6789
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using MST1/STK4 Rabbit pAb (CAB8043) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
