The STK39 Polyclonal Antibody (CAB2275) is a valuable tool for researchers studying STK39, a protein kinase that plays a key role in various cellular processes, including ion transport and cell proliferation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the STK39 protein, this antibody enables precise detection and analysis in a wide range of cell types, making it an essential component for studies in molecular biology and disease research.STK39, also known as STE20/SPS1-related proline/alanine-rich kinase, is critically involved in regulating ion channels and maintaining cellular homeostasis.
Dysregulation of STK39 has been linked to various diseases, including hypertension, kidney disorders, and cancer. By investigating the function of STK39, researchers can gain insight into the mechanisms underlying these conditions and develop targeted therapies to effectively treat them.The STK39 Polyclonal Antibody offers a reliable tool for researchers seeking to unravel the complexities of STK39 biology and its implications in human health and disease. Its high specificity and sensitivity make it an indispensable resource for advancing our understanding of this important protein kinase and its role in various physiological and pathological processes.
Product Name:
STK39 Rabbit Monoclonal Antibody
SKU:
CAB2275
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 401-545 of human STK39 (Q9UEW8).
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.
Purification Method:
Affinity purification
Gene ID:
27347
Clone Number:
ARC1896
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using STK39 Rabbit mAb (CAB2275) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
