The STK38 Polyclonal Antibody (CAB8191) is a valuable tool for researchers studying the STK38 protein, a serine/threonine kinase known for its involvement in cell signaling pathways and cellular processes. Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the STK38 protein, this antibody allows for the detection and analysis of STK38 in various cell types, making it an essential component for studies in cell biology and cancer research.STK38, also known as NDR1, plays a crucial role in regulating cell growth, proliferation, and apoptosis. Dysregulation of STK38 has been linked to various diseases, including cancer and neurodegenerative disorders, making it an attractive target for therapeutic intervention.
By understanding the function and activity of STK38, researchers can potentially develop new treatments and strategies for combating these conditions.Overall, the STK38 Polyclonal Antibody (CAB8191) is a valuable tool for researchers interested in exploring the role of STK38 in cellular signaling pathways and disease development. Its high specificity and reactivity make it a reliable option for Western blot experiments and other research applications in the fields of cell biology and cancer research.
Product Name:
STK38 Rabbit Polyclonal Antibody
SKU:
CAB8191
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 366-465 of human STK38 (NP_009202.1).
Sequence:
ILKP TVAT SNHP ETDY KN
Tested Applications:
WBIF/ICCELISA
Recommended Dilution:
WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:
NDR; NDR1; STK38
Positive Sample:
U-937,Rat spleen
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
54kDa
Observed MW:
54kDa
This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
11329
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using STK38 Rabbit pAb (CAB8191) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
