The STK3 Rabbit Monoclonal Antibody (CAB9036) is a valuable tool for researchers studying STK3, a protein kinase involved in cell signaling pathways and regulation of cell growth. This antibody, generated in rabbits, demonstrates high specificity and sensitivity for STK3 detection in human samples, making it ideal for use in Western blot experiments.STK3, also known as MST2, plays a crucial role in various cellular processes including apoptosis, cell proliferation, and cytoskeletal rearrangement. Dysregulation of STK3 has been implicated in cancer development and progression, highlighting its importance as a target for therapeutic interventions.
By using this antibody, researchers can effectively investigate the function and expression levels of STK3 in different cell types, providing valuable insights for cancer research and drug development efforts.Overall, the STK3 Rabbit Monoclonal Antibody (CAB9036) offers a reliable tool for studying the biological functions of STK3 and its potential implications in disease pathogenesis. Its high specificity and sensitivity make it a valuable asset for researchers conducting experiments in the fields of cell signaling, cancer biology, and drug discovery.
Product Name:
STK3/MST2 Rabbit Monoclonal Antibody
SKU:
CAB9036
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human STK3/MST2 (Q13188).
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6788
Clone Number:
ARC1389
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using STK3/MST2 Rabbit mAb (CAB9036) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
