STK3/MST2 Rabbit Polyclonal Antibody (CAB6992)
- SKU:
- CAB6992
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | STK3/MST2 Rabbit Polyclonal Antibody |
SKU: | CAB6992 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 323-450 of human STK3/MST2 (NP_006272.2). |
Sequence: | SHTM VKTS VESV GTMR ATST MSEG AQTM IEHN STML ESDL GTMV INSE DEEE EDGT MKRN ATSP QVQR PSFM DYFD KQDF KNKS HENC NQNM HEPF PMSK NVFP DNWK VPQD GDFD FLKN LSLE ELQM |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | KRS1; MST2; STK3/MST2 |
Positive Sample: | 293T,HeLa,Jurkat,MCF7,NIH/3T3,Mouse liver,Mouse brain,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 56kDa |
Observed MW: | 65kDa, 37kDa |
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6788 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |