The STK3 Polyclonal Antibody (CAB6992) is a valuable tool for researchers studying STK3, a serine/threonine protein kinase involved in cellular processes such as cell proliferation and apoptosis. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for various research applications, including Western blot analysis.STK3, also known as MST2, plays a crucial role in regulating cell growth and survival, making it a key player in cancer research and drug development.
By targeting STK3, researchers can investigate its involvement in signaling pathways and its potential as a therapeutic target for various diseases.Overall, the STK3 Polyclonal Antibody is a reliable tool for studying STK3 protein expression and function in different cell types, providing valuable insights into its role in health and disease. Its versatility and specificity make it a valuable asset for researchers in the fields of molecular biology, oncology, and drug discovery.
Product Name:
STK3/MST2 Rabbit Polyclonal Antibody
SKU:
CAB6992
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 323-450 of human STK3/MST2 (NP_006272.2).
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6788
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using STK3/MST2 antibody (CAB6992) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
