STK17A Antibody (PACO19582)
- SKU:
- PACO19582
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
STK17A Antibody (PACO19582)
The STK17A Polyclonal Antibody (PAC019582) is a valuable tool for researchers studying the STK17A protein, which plays a role in regulating cell death and survival pathways. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.STK17A, also known as DRAK1, is involved in apoptosis and autophagy processes, making it a key player in cellular homeostasis and survival. Research into STK17A is important for understanding cell signaling pathways and developing therapies for diseases like cancer and neurodegenerative disorders.
By using the STK17A Polyclonal Antibody, researchers can detect and analyze the expression of STK17A in a variety of cell types, providing valuable insights into its function and potential as a therapeutic target. This antibody is a valuable tool for studies in molecular biology, cell signaling, and cancer research.
| Antibody Name: | STK17A Antibody (PACO19582) |
| Antibody SKU: | PACO19582 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human STK17A |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19582(STK17A Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO19582(STK17A Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. |
| Synonyms: | serine/threonine kinase 17a |
| UniProt Protein Function: | DRAK1: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.Protein type: Kinase, protein; Protein kinase, CAMK; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); CAMK group; DAPK familyChromosomal Location of Human Ortholog: 7p13Cellular Component: nucleusMolecular Function: protein serine/threonine kinase activity; ATP bindingBiological Process: apoptosis; positive regulation of apoptosis; protein amino acid phosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UEE5 |
| NCBI GenInfo Identifier: | 109255245 |
| NCBI Gene ID: | 9263 |
| NCBI Accession: | NP_004751.2 |
| UniProt Secondary Accession: | Q9UEE5,Q8IVC8, A4D1V6 |
| UniProt Related Accession: | Q9UEE5 |
| Molecular Weight: | 46,558 Da |
| NCBI Full Name: | serine/threonine-protein kinase 17A |
| NCBI Synonym Full Names: | serine/threonine kinase 17a |
| NCBI Official Symbol: | STK17AÂ Â |
| NCBI Official Synonym Symbols: | DRAK1Â Â |
| NCBI Protein Information: | serine/threonine-protein kinase 17A; DAP kinase-related apoptosis-inducing protein kinase 1; death-associated protein kinase-related 1; serine/threonine kinase 17a (apoptosis-inducing) |
| UniProt Protein Name: | Serine/threonine-protein kinase 17A |
| UniProt Synonym Protein Names: | DAP kinase-related apoptosis-inducing protein kinase 1 |
| Protein Family: | |
| UniProt Gene Name: | STK17AÂ Â |
| UniProt Entry Name: | ST17A_HUMAN |
| Antibodies |
| STK17A Antibody (PACO12529) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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