[KO Validated] LKB1 Rabbit Polyclonal Antibody (CAB2122)
- SKU:
- CAB2122
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | [KO Validated] LKB1 Rabbit Polyclonal Antibody |
SKU: | CAB2122 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 134-433 of human LKB1 (NP_000446.1). |
Sequence: | CGMQ EMLD SVPE KRFP VCQA HGYF CQLI DGLE YLHS QGIV HKDI KPGN LLLT TGGT LKIS DLGV AEAL HPFA ADDT CRTS QGSP AFQP PEIA NGLD TFSG FKVD IWSA GVTL YNIT TGLY PFEG DNIY KLFE NIGK GSYA IPGD CGPP LSDL LKGM LEYE PAKR FSIR QIRQ HSWF RKKH PPAE APVP IPPS PDTK DRWR SMTV VPYL EDLH GADE DEDL FDIE DDII YTQD FTVP GQVP EEEA SHNG QRRG LPKA VCMN GTEA AQLS TKSR AEGR APNP ARKA CSAS SKIR RLSA CKQQ |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PJS; LKB1; hLKB1 |
Positive Sample: | MCF7,293T,Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane, Mitochondrion, Nucleus. |
Calculated MW: | 49kDa |
Observed MW: | 49-60kDa |
The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers.
Purification Method: | Affinity purification |
Gene ID: | 6794 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |